Cannabinoids as Weight Loss Drugs Part II

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The association between cannabis and appetite is well known both in the scientific world and pop culture. As many of our longtime blog readers already know, this association ultimately led to the development of one of the most horrific weight…

How Chronic Stress Impairs the Endocannabioid System

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In general, research into the body’s endocannabinoid system proceeds via administering a substance like a cannabinoid or another drug, and recording the impact of that administration on a specific behavior or physiological process. However,…

Facts and Myths of Schizophrenia and Cannabis

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Critics of medical cannabis use often bring up the association between cannabis use and mental illness. In this context, the implication is almost always that cannabis use is unsafe and can exacerbate or initiate psychotic symptoms in both healthy…

The Hunt to Establish New Cannabinoid Receptors: G Protein Pathways

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For readers of the blog, we’ve always broken the endocannabinoid system down as follows: cannabinoids (from plants, labs, or produced in the human body) cannabinoid receptors (two kinds, CB1 and CB2) enzymes that break down cannabinoids Readers…

Anandamide

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Up to this point, we haven’t spoken much of the body’s own endocannabinoids. As a quick refresher, the endocannabinoid system consists of receptors and enzymes that metabolize any cannabinoids bonding to those receptors. However, our cannabinoid…

Allosteric Modulation: The Versatility of Cannabinoid Receptors

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These are exciting times for a cannabinoid researcher; new information must constantly be integrated with the growing body of knowledge surrounding the endocannabinoid system. At times, that new information can even flip our understanding of…

Seeing is Believing: ICRS

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Greetings readers, we’ve just returned from the 2015 International Cannabinoid Research Society (ICRS) conference. ICRS describes itself as “a non-political, non-religious organization dedicated to scientific research in all fields of the…

Cannabinoids in Pain Management, A Review

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Pain management is one of our most revisited topics here on the Cornerstone blog. Our commitment to reporting studies related to pain management should come as no surprise to readers; pain relief accounts for a substantial portion of all medical…

Inhibiting Re-Uptake To Enable Treatment: The Endocannabinoid System and New Medicines

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In popular culture, we like to think of an inventor as someone who notices a problem, thinks really hard about a solution, and solves that problem with a novel device or approach. Oftentimes however, discovery proceeds in reverse: first a solution…

Can Cannabis Lower Blood Pressure?

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Cannabis has historically been thought of as a relaxant and a depressant of the physical body. As a result it’s no surprise that the idea of using cannabis to help manage blood pressure has gained some traction recently. While generally confirming…