The Hunt to Establish New Cannabinoid Receptors: G Protein Pathways

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For readers of the blog, we’ve always broken the endocannabinoid system down as follows:cannabinoids (from plants, labs, or produced in the human body) cannabinoid receptors (two kinds, CB1 and CB2) enzymes that break down cannabinoidsReaders…

Anandamide

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Up to this point, we haven’t spoken much of the body’s own endocannabinoids. As a quick refresher, the endocannabinoid system consists of receptors and enzymes that metabolize any cannabinoids bonding to those receptors. However, our cannabinoid…

Allosteric Modulation: The Versatility of Cannabinoid Receptors

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These are exciting times for a cannabinoid researcher; new information must constantly be integrated with the growing body of knowledge surrounding the endocannabinoid system. At times, that new information can even flip our understanding of…

Seeing is Believing: ICRS

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Greetings readers, we’ve just returned from the 2015 International Cannabinoid Research Society (ICRS) conference. ICRS describes itself as “a non-political, non-religious organization dedicated to scientific research in all fields of the…

Cannabinoids in Pain Management, A Review

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Pain management is one of our most revisited topics here on the Cornerstone blog. Our commitment to reporting studies related to pain management should come as no surprise to readers; pain relief accounts for a substantial portion of all medical…

Inhibiting Re-Uptake To Enable Treatment: The Endocannabinoid System and New Medicines

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In popular culture, we like to think of an inventor as someone who notices a problem, thinks really hard about a solution, and solves that problem with a novel device or approach. Oftentimes however, discovery proceeds in reverse: first a solution…

Can Cannabis Lower Blood Pressure?

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Cannabis has historically been thought of as a relaxant and a depressant of the physical body. As a result it’s no surprise that the idea of using cannabis to help manage blood pressure has gained some traction recently. While generally confirming…

Treating ADHD with Cannabinoids

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Chances are that you or someone you know has been diagnosed with Attention-Deficit Hyperactivity Disorder (ADHD). ADHD is one of the most commonly diagnosed neurological conditions as well as one of the most controversial due to the difficulty…

THCV. Forget What You've Heard

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One of the biggest obstacles to responsible proponents of medical cannabis is the amount of misinformation we have to contend with from both sides. On one side there are  government-sponsored publications that directly misconstrue the science…

Whole Plant CBD More Effective Than Pure CBD?

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At Cornerstone, we talk frequently about dosing, not just because it’s important to members, but also because it’s important to us. The end goal is for every patient to experience the maximum benefit of medical cannabis. Although it seems…